The natural history and treatment of non-functioning pituitary adenomas (non-functioning PitNETs)
نویسندگان
چکیده
منابع مشابه
Prevalence, Clinical Features, and Natural History of Incidental Clinically Non-Functioning Pituitary Adenomas.
The objective of the study was to assess the prevalence and clinical features of incidentally discovered clinically non-functioning pituitary adenoma (CNFPA) and to analyze its natural history. A multicenter retrospective study in patients diagnosed with incidental CNFPA periodically followed-up in 3 specialized neuroendocrinology units from 1992 to 2015 was performed. Out of a total of 189 CNF...
متن کاملExpression of genes FOLR1, BAG1 and LAPTM4B in functioning and non-functioning pituitary adenomas.
INTRODUCTION The mechanism of pathogenesis of adenomas pituitary is still unknown; differences between pituitary cells of different origin are observed. Identification of genes specific to pituitary adenomas should give better understanding of differences in their response to therapy, especially to radiotherapy. The aim of our study was to independently validate differences in the expression of...
متن کاملGender-related differences in non-functioning pituitary adenomas.
OBJECTIVES Clinically non-functioning pituitary adenomas are common tumors of the pituitary gland. No studies have yet documented gender-related differences in the growth and presentation of these tumors and nothing is known about their effects on their subsequent surgical outcome and prognosis. SETTING AND DESIGN Twenty-eight patients with non-functioning pituitary adenoma, that met strict i...
متن کاملMedical therapy for clinically non-functioning pituitary adenomas.
Surgery is the first-line treatment of patients with clinically non-functioning pituitary adenomas (NFAs). Because of lack of clinical syndrome these tumours are diagnosed with a variable delay, when patients suffer from compression symptoms (hypopituitarism, headache and visual field defects) due to the extension of the tumour outside the pituitary fossa. Surgery is followed by residual tumour...
متن کامل[Non-functioning gangliocytoma of the pituitary gland].
Pituitary gangliocytomas are uncommon benign tumors (less than 100 cases have been reported to date)1-6 with a low proliferation potential and a slow growth. Histologically, most pituitary gangliocytomas are mixed tumors consisting of neuronal ganglion cells and an adenomatous proliferation of adenohypophyseal cells4,7,8; both components may occur as a single nodule or coexist as separate but a...
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ژورنال
عنوان ژورنال: Endocrine-Related Cancer
سال: 2020
ISSN: 1351-0088,1479-6821
DOI: 10.1530/erc-20-0136